Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older adult women

Authors

DOI:

https://doi.org/10.26124/bec:2022-0002

Keywords:

platelets, resting metabolic rate (RMR), cardiopulmonary exercise testing (CPET), OXPHOS capacity, electron transfer capacity, inverted regression analysis

Summary

This study investigates relationships between platelet mitochondrial bioenergetics and resting metabolic rate (RMR), body composition, and exercise fitness in older adult women. We report positive correlations between peak respiratory exchange ratio (RER) and RMR with five measures of platelet respiration, supporting the premise that blood cells can be utilized to report on mitochondrial function associated with physical health and fitness. Identifying mechanisms associated with physical performance among older adults supports the development of reliable biomarkers of healthy aging and can advance the development of efficacious interventions.

Cite:

Heimler SR, Phang HJ, Bergstrom J, Mahapatra G, Dozier S, Gnaiger E, Molina AJA (2022). Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older women. Bioenerg Commun 2022.2. https://doi.org/10.26124/bec:2022-0002

Published

2022-06-28

Issue

Section

Living Communications