Metabolic Health and Obesity: The Essential Role of Mitochondrial Function

Abstract

The management of obesity is critical and has traditionally included surgical interventions like bariatric surgery and pharmacological treatments. However, these methods have limitations when applied in isolation, which limits their effectiveness in completely reversing the condition. A comprehensive approach that considers the unique properties of adipose tissue and evaluates additional parameters can offer a more nuanced understanding of obesity. Moreover, lifestyle modifications have been shown to significantly influence the performance of cellular organelles responsible for maintaining bodily homeostasis, including mitochondria. This perspective delves into the impact of obesity on mitochondrial function and examines how lifestyle changes, in conjunction with current treatments, can influence this relationship.

CITE:

Cutanda-Tesouro S, Alvarez-Luis J, Gama-Perez P, Garcia-Roves PM (2025) Metabolic Health and Obesity: The Essential Role of Mitochondrial Function. Bioenerg Commun 2025.8. https://doi.org/10.26124/becprep.2025-0008