A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part?

Autori

  • Atan Gross Weizmann Institute of Science, IL

DOI:

https://doi.org/10.26124/bec:2024-0001

Ključne reči:

MTCH2, BID, energy metabolism, mitochondrial fusion, ER-mitochondria crosstalk, apoptosis, scramblase, insertase

Apstrakt

Mitochondrial carrier homolog 2 (MTCH2) is currently one of the most enigmatic mitochondrial proteins. MTCH2’s ligand is the pro-apoptotic BID protein, and the love story between these two proteins involves the regulation of diverse cellular processes including apoptosis, energy metabolism, mitochondrial dynamics, and protein insertion into the mitochondrial outer membrane. This review offers an updated progress report of these two proteins and describes our hypotheses regarding their joint mechanism of action.

Cite:

Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001

 

Preuzimanja

Dodatni fajlovi

Objavljeno

2024-02-08

Broj časopisa

God. 2024

Rubrika

Living Communications

Kategorije

Licenca

Sva prava zadržana (c) 2024 Atan Gross

Creative Commons License

Ovaj rad je pod Creative Commons Aуторство-Nekomercijalno-Bez prerade 4.0 Internacionalna licenca.

Kako citirati

Gross, A. (2024). A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenergetics Communications, 2024, 1. https://doi.org/10.26124/bec:2024-0001