OXPHOS coupling and uncoupling

Аутори

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https://doi.org/10.26124/bec.2024-0005

Кључне речи:

electron transfer capacity, LEAK respiration, mitochondria, oxidative phosphorylation

Апстракт

Coupling of OXPHOS is classically studied by comparing ADP-stimulated O2 flux (OXPHOS capacity P at saturating ADP and Pi concentrations) with non-phosphorylating LEAK respiration L, maintained mainly to compensate for the proton leak at high chemiosmotic potential in mitochondrial preparations supplied with fuel substrates to support mitochondrial electron transfer. However, measurement of the non-coupled electron transfer capacity E (ET capacity at collapsed chemiosmotic potential) yields additional information on coupling, since ET capacity may exceed OXPHOS capacity.

Cite:

Cardoso LHD, Gnaiger E (2024) OXPHOS coupling and uncoupling. Bioenerg Commun 2024.5. https://doi.org/10.26124/bec.2024-0005

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Објављено

2024-08-09

Број часописа

Год. 2024

Рубрика

Living Communications

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Лиценца

Сва права задржана (c) 2024 Luiza Helena Daltro Cardoso, Erich Gnaiger

Creative Commons License

Овај рад је под Creative Commons Aуторство-Nекомерцијално-Без прераде 4.0 Интернационална лиценца.

Како цитирати

Cardoso, L. H. D., & Gnaiger, E. (2024). OXPHOS coupling and uncoupling . Bioenergetics Communications, 2024, 5. https://doi.org/10.26124/bec.2024-0005