A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part?

Autor

  • Atan Gross Weizmann Institute of Science, IL

DOI:

https://doi.org/10.26124/bec:2024-0001

Słowa kluczowe:

MTCH2, BID, energy metabolism, mitochondrial fusion, ER-mitochondria crosstalk, apoptosis, scramblase, insertase

Abstrakt

Mitochondrial carrier homolog 2 (MTCH2) is currently one of the most enigmatic mitochondrial proteins. MTCH2’s ligand is the pro-apoptotic BID protein, and the love story between these two proteins involves the regulation of diverse cellular processes including apoptosis, energy metabolism, mitochondrial dynamics, and protein insertion into the mitochondrial outer membrane. This review offers an updated progress report of these two proteins and describes our hypotheses regarding their joint mechanism of action.

Cite:

Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001

 

Pobrania

Pliki dodatkowe

Opublikowane

2024-02-08

Numer

Tom 2024

Dział

Living Communications

Kategorie

Licencja

Prawa autorskie (c) 2024 Atan Gross

Creative Commons License

Utwór dostępny jest na licencji Creative Commons Uznanie autorstwa – Użycie niekomercyjne – Bez utworów zależnych 4.0 Międzynarodowe.

Jak cytować

Gross, A. (2024). A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenergetics Communications, 2024, 1. https://doi.org/10.26124/bec:2024-0001