The bioenergetic landscape of respiratory flux control: mapping the scope of metabolic flexibility and mitochondrial fitness

Kirjoittajat

DOI:

https://doi.org/10.26124/bec2026-0005

Avainsanat:

bioenergetic cluster analysis, coupling efficiency, electron transfer, excess capacity, leak respiration, oxidative capacity, oxidative phosphorylation, routine respiration, routine-ATP coupling ratio, routine-ATP control efficiency

Abstrakti

Contribution to MiP2026

Cite: Gnaiger E (2026) The bioenergetic landscape of respiratory flux control: mapping the scope of metabolic flexibility and mitochondrial fitness. Bioenerg Commun 2026.5 https://doi.org/10.26124/bec2026-0005

Lähdeviitteet

Hütter E, Renner K, Pfister G, Stöckl P, Jansen-Dürr P, Gnaiger E (2004) Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts. Biochem J 380:919-28. https://doi.org/10.1042/BJ20040095

Gnaiger E (2025) Mitochondrial respiratory function in living cells. Bioenerg Commun 2025.5. https://doi.org/10.26124/bec.2025-0005

Gnaiger E (2026) Mapping metabolic flexibility by respiratory flux control: Bioenergetic cluster analysis of mitochondrial fitness. BEC preprints 2026.5. https://doi.org/10.26124/becprep.2026-0005

Timón-Gómez A, Doerrier C, Sumbalová Z, Garcia-Souza LF, Baglivo E, Cardoso LHD, Gnaiger E (2026) Bioenergetic profiles and respiratory control in mitochondrial physiology: Precision analysis of oxidative phosphorylation. Exp Physiol 111:179-211. https://doi.org/10.1113/EP092792

Hochachka PW, Somero GN (2002) Biochemical adaptation: mechanism and process in physiological evolution. Oxford Univ Press, New York: 466 pp.

Debevec T, Longman DP, Bourgois JG (2024) Defining adaptation within applied physiology - is there room for improvement? Front Physiol 15:1459026. https://doi.org/10.3389/fphys.2024.1459026

Tanaka H, Seals DR (2024) Scientific writing in physiology: Confused/misused terms and phrases. J Appl Physiol (1985) 136:401-7. https://doi.org/10.1152/japplphysiol.00868.2023

Julkaistu

2026-11-12

Numero

Osasto

Living Communications

Kategoriat

Viittaaminen

Gnaiger, E. (2026). The bioenergetic landscape of respiratory flux control: mapping the scope of metabolic flexibility and mitochondrial fitness. Bioenergetics Communications, 2026, 5. https://doi.org/10.26124/bec2026-0005