A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part?

Egileak

  • Atan Gross Weizmann Institute of Science, IL

DOI:

https://doi.org/10.26124/bec:2024-0001

Gako-hitzak:

MTCH2, BID, energy metabolism, mitochondrial fusion, ER-mitochondria crosstalk, apoptosis, scramblase, insertase

Laburpena

Mitochondrial carrier homolog 2 (MTCH2) is currently one of the most enigmatic mitochondrial proteins. MTCH2’s ligand is the pro-apoptotic BID protein, and the love story between these two proteins involves the regulation of diverse cellular processes including apoptosis, energy metabolism, mitochondrial dynamics, and protein insertion into the mitochondrial outer membrane. This review offers an updated progress report of these two proteins and describes our hypotheses regarding their joint mechanism of action.

Cite:

Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001

 

Deskargak

Fitxategi gehigarriak

Argitaratua

2024-02-08

Zenbakia

Libk. 2024

Atala

Living Communications

Kategoriak

Lizentzia

Egile-eskubideak 2024 Atan Gross

Creative Commons License

Lan hau Creative Commons Aitortu-EzKomertziala-LanEratorririkGabe 4.0 Nazioarteko Lizentziapean dago argitaratuta.

Aipuak nola egin

Gross, A. (2024). A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenergetics Communications, 2024, 1. https://doi.org/10.26124/bec:2024-0001