Published November 8, 2021 | Version v1
Journal article Open

Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria

  • 1. Oroboros Instruments, Innsbruck, Austria
  • 2. Biochemistry and Medicine, School of Life Sciences, Univ Sussex, Falmer, Brighton, UK
  • 3. Dept Structural and Molecular Biol, Univ College London, London, UK
  • 4. Oroboros Instruments, Innsbruck, Austria; Dept Visceral, Transplant, and Thoracic Surgery, D. Swarovski Research Laboratory, Medical Univ Innsbruck, Innsbruck, Austria.

Description

This material is linked to the preprint:

Komlódi T, Cardoso LHD, Doerrier C, Moore AL, Rich PR, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. MitoFit Preprints 2021.2.v4. doi:10.26124/mitofit:2021-0002.v4

 

All DatLab files (.DLD extension) containing the raw data of oxygen calibration, instrumental oxygen background tests, SUIT-006 and SUIT-031 experiments (oxygen concentration/flux and CoQ redox state) that were used for the publication are available here.

Figure 2: 2019-08-28 PQ1-01.DLD, 2019-08-28 PQ2-01.DLD, 2019-08-28 PQ3-01.DLD, 2020-04-21 PN2-01.DLD, 2020-04-21 PQ2-01.DLD, 2020-04-24 PN1-01.DLD, 2020-08-10 P2-01.DLD, 2020-08-10 P3-01.DLD, 2020-08-10 P9-01.DLD, 2020-08-12 P1-01.DLD, 2020-08-12 P5-01.DLD,2020-08-12 P6-01.DLD, 2020-09-08 P4-01.DLD, 2020-09-22 P10-01.DLD, 2020-10-27 P7-01.DLD, 2020-10-27 P8-01.DLD. Figure 3: 2019-06-14 PQ2-01.DLD. Figure 4 and 5: 2019-09-12 PQ1-02.DLD. Figure 6: Respiration with and without CoQ2.xlsx; Figure 7: 2021-10-21 PN4-03.DLD, 2021-10-21 PN5-02.DLD, 2021-10-21 PQ2-02.DLD. Figure 8:2019-09-12 PQ1-02.DLD, 2019-09-12 PQ2-03.DLD, 2019-09-12 PQ3-02.DLD. Reduced Q fraction imt brain.xlsx; Reduced Q fraction imt heart.xlsx.

Notes

This work was funded by the European Union's Horizon 2020 research and innovation programme under grant agreement No. 859770, NextGen-O2k project.

Files

Files (177.4 MB)

Name Size Download all
md5:0429046cff77550e1466677178b61d70
5.1 MB Download
md5:1e320ed0bdfb7af4311172635668fc91
6.8 MB Download
md5:296c75ef46f44301004422f1cfdc07f0
6.8 MB Download
md5:6c0f46fa2671e656b384a10586013f0a
6.8 MB Download
md5:fbbc4a30a75692bff99088045fa1bc7f
4.6 MB Download
md5:6bfe9581787ed396677af95c3f69b1de
5.1 MB Download
md5:cfe0fb979dfb9f4432f61c8d44e2d2e4
4.6 MB Download
md5:8e4a14bb694a5b13df4b848d531e95b9
5.1 MB Download
md5:5cd92905a05f01b99bec0d4772c04e9d
4.6 MB Download
md5:c6b00a68c8c73a2fc51533fc91ae792e
5.6 MB Download
md5:ae7e8e0770993fc8fe6a84ee1a4860c4
5.6 MB Download
md5:7f9b6cae5dce605cf5fb819c247f04e1
5.6 MB Download
md5:c94072d4c062f8cc6f908888639441f3
5.6 MB Download
md5:251cc98cdf8c322df1994e008e4bf648
4.6 MB Download
md5:f9e1cafc471e8ca42ced13cc1f517590
5.1 MB Download
md5:aee72bc12b0395740bd67bb5b63eb1db
4.6 MB Download
md5:bd2f65aa2e2a703b5d42a912d3d7e346
5.1 MB Download
md5:d307e065306890c502c6c38ee4e240d2
4.6 MB Download
md5:c6d1cfd8dda35f8da4a40c52c9124506
5.1 MB Download
md5:6c3013dd6aa1547d33085103eb604335
8.1 MB Download
md5:c26b0e931e89658b1c45ddfce6f44144
5.6 MB Download
md5:0e5a257a77a580d95706c506a7ba8a7a
5.6 MB Download
md5:9fff1ad45f7a7e8f7bd29ebb5b1196b8
8.1 MB Download
md5:1185a85dd8b2e365399e032fe3a6bc4b
5.6 MB Download
md5:6facef0b440278e70b538a866629f46f
5.6 MB Download
md5:2c87a0d46973e8cce77e361f34e3acb0
5.6 MB Download
md5:8ae5dbac18e53e120e4602450dffcf33
5.6 MB Download
md5:e918f85b05acab925e09d52e7bf7fa00
5.6 MB Download
md5:90d6a3fb9d35c0f9902af1792304d0ba
5.6 MB Download
md5:c985f623090a0321d186016fdc5c878d
5.1 MB Download
md5:ed51d95b47bb26a441f30aa430b6ae6f
4.6 MB Download
md5:a2c9cd614ba1547a5eb4a3a4b63dd9b3
5.1 MB Download
md5:33845f8e37f6bd7e8c0a99cb7fd3d49c
149.3 kB Download
md5:a72c140eeed9c40e9fb0a8d744e67f39
112.2 kB Download
md5:b9243719d634f8eb32bef8b21e3be49b
22.9 kB Download