A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part?

المؤلفون

  • Atan Gross Weizmann Institute of Science, IL

DOI:

https://doi.org/10.26124/bec:2024-0001

الكلمات المفتاحية:

MTCH2، BID، energy metabolism، mitochondrial fusion، ER-mitochondria crosstalk، apoptosis، scramblase، insertase

الملخص

Mitochondrial carrier homolog 2 (MTCH2) is currently one of the most enigmatic mitochondrial proteins. MTCH2’s ligand is the pro-apoptotic BID protein, and the love story between these two proteins involves the regulation of diverse cellular processes including apoptosis, energy metabolism, mitochondrial dynamics, and protein insertion into the mitochondrial outer membrane. This review offers an updated progress report of these two proteins and describes our hypotheses regarding their joint mechanism of action.

Cite:

Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001

 

الملفات الإضافية

منشور

2024-02-08

إصدار

القسم

Living Communications

الفئات

كيفية الاقتباس

Gross, A. (2024). A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenergetics Communications, 2024, 1. https://doi.org/10.26124/bec:2024-0001