Count

From Bioblast
Jump to: navigation, search
Bioblasts - Richard Altmann and MiPArt by Odra Noel
MitoPedia         Terms and abbreviations         Concepts and methods         MitoPedia: SUIT         MiP and biochemistry         Preprints and history



MitoPedia

Count

Description

Count-vs-number.png

Count NX is the number N of elementary entities of entity-type X. The single elementary entity UX is a countable object or event. NX is the number of objects of type X, whereas the term 'entity' and symbol X are frequently used and understood in dual-message code indicating both (1) the entity-type X and (2) a count of NX = 1 x for a single elementary entity UX. 'Count' is synonymous with 'number of entities' (number of particles such as molecules, or objects such as cells). Count is one of the most fundamental quantities in all areas of physics to biology, sociology, economy and philosphy, including all perspectives of the statics of countable objects to the dynamics of countable events. The term 'number of entities' can be used in short for 'number of elementary entities', since only elementary entities can be counted, and as long as it is clear from the context, that it is not the number of different entity types that are the object of the count.

Abbreviation: NX [x]

Reference: Gnaiger 2020 MitoPathways, BEC2020.1

Communicated by Gnaiger Erich (2019-08-15) last update 2020-07-23
in: Anastrophe XX Entity X and elementary unit x of A X-mass Carol

Number, count, and recount

In the International System of Units (SI), the quantity 'count' is explicitly considered as an exception: "Each of the seven base quantities used in the SI is regarded as having its own dimension. .. All other quantities, with the exception of counts, are derived quantities" (Bureau International des Poids et Mesures 2019 The International System of Units (SI)). Count is not included in the SI as a base quantity. Since 2019-05-20, the amount of substance, n, of a system is defined as "a measure of the number of specified elementary entities. An elementary entity may be an atom, a molecule, an ion, an electron, any other particle or specified group of particles" (Bureau International des Poids et Mesures 2019). The quantity 'amount', n, therefore, is a number of specified elementary entities expressed in the unit 'mole' [mol] with dimension N. Logically, the quantities 'amount' and 'count' have exactly identical meanings, since the quantity 'count' NX is a number of specified elementary entities expressed in the unit 'elementary unit' [x] with dimension X. Similarly, charge is a derived SI unit with dimension A·T, converting the elementary unit [x] into coulombs [C] using the elementary charge.
'Count' NX (number of entities UX) and 'number' N are distinguished (German: Anzahl versus Zahl). A count is a quantity represented by a number N and the corresponding entity-type X (cell count: Nce). In contrast, a number is represented by numerals only, is a mathematical object used for counting, and is thus not a physicochemical quantity. Neither is a defined elementary entity-type X a count, it is rather the dimension of a count (entity type: cell, ce). Not all sample types contain countable objects. Countable objects are physicochemical particles (atoms, electrons, ions, molecules), ensembles (packaging units, parcels), biological entities (cells, organisms, individuals, patients), and units of transmitted information. The magnitude of a count is expressed by a number times the elementary unit [x]. The name 'elementary unit' is proposed for the unit [x]. x ('times') indicates in dynamics how many times a defined event is 're-counted' during a defined period of time, and in statics how many times different members of the defined entity-type are accounted for in a defined system. It is important not to mix statics with dynamics; the count of statics counts different members of the defined entity in the system, but does not re-count the same member of the defined entity in the system (consider the political problem of counting votes).
Counts per volume of a mixture is a concentration [x·m-3] or [x·L-1]. Counts per area is an elementary area-density [x·m-2]. In dynamics, counts per time is a frequency, NX·t-1 [x·s-1]. Converting the time t travelled into distance l, counts per length can be considered as a distance-frequency NX·l-1 [x·m-1]. Compare the dynamic question on how many steps you take per second when you walk or run, with the static question on how many steps you take per 1 km distance covered. This expression in normal form is generally understandable, as expressed in canonical form: How many numbers Nstep of entities of entity-type 'steps' do you count per second when you walk or run? How many numbers Nsteps of entities of entity-type steps do you count per km when you move a distance of on km?
SI prefixes are used with SI units, such as [kg], [µmol], [nm], [MHz]. Prefixes cannot be used with numbers. However, prefixes can be used with the elementary unit [x], applying the same convention for any symbol of SI units: Mx = 106 x; MHz = Mx·s-1; µx = 10-6 x; Gx = 109 x; nx = 10-9 x. If appropriate, it is convenient in statics to write simply 'unit' instead of 'elementary unit', and in dynamics to use 'times' instead of 'elementary unit'. Examples: Avogadro constant NA, expressed in 'elementary units per mole' [x·mol-1]; elementary charge e, expressed in 'coulombs per elementary unit' [C·x-1]; body mass is mass per single elementary body (not mass of several bodies) expressed in 'kilograms per unit' [kg·x-1]; frequency (counts per time, NX/t), expressed in 'units per second' (times per second) [x·s-1].


Base quantities and count

SI-units.png
Quantity Symbol for quantity Q Symbol for dimension Name of SI unit Symbol for SI unit uQ [*]
length l L meter m
mass m M kilogram kg
time t T second s
electric current I I ampere A
thermodynamic temperature T Θ kelvin K
amount of substance *,§ nX = NX·NA-1 N mole mol
count *,$ NX X elementary unit x
elementary entity *,$ UX U elementary unit x
charge *,€ Qe = NX·zX·e I·T coulomb C = A·s
luminous intensity Iv J candela cd
[*] »SI base units, except for the canonical 'elementary unit' [x]. The following footnotes are canonical comments.
* For the quantities n, N, U, and Q, the entity-type X of the elementary entity UX has to be specified in the text and indicated by a subscript: nO2; Nce; Qe.
§ Amount nX is an elementary quantity, converting the elementary unit [x] into moles [mol] using the Avogadro constant, NA.
$ Count NX equals the number of elementary entities UX. In the SI, the quantity 'count' is explicitly considered as an exception: "Each of the seven base quantities used in the SI is regarded as having its own dimension. .. All other quantities, with the exception of counts, are derived quantities" (Bureau International des Poids et Mesures 2019 The International System of Units (SI)). An elementary entity UX is not a count (UX is not a number of UX). NX has the dimension X of a count and UX has the dimension U of an elementary entity, and both quantities have the same unit, the 'elementary unit' [x].
Charge is a derived SI quantity. Charge is an elementary quantity, converting the elementary unit [x] into coulombs [C] using the elementary charge, e, or converting moles [mol] into coulombs [C] using the Faraday constant, F. zX is the charge number of elementary entity UX, which is a constant for any defined elementary entity UX. Qe = nX·zX·F

SI and IUPAC

Unfortunately, the elementary unit [x] is not explicitly considered by the SI and IUPAC (Mohr and Philipps 2015). This causes confusion since then, for example, the unit 'joule' [J] relates without discrimination to both: (1) exergy per elementary entity, and (2) exergy of the system (instrumental chamber) or the (sub)sample in the system. In contrast, joule per elementary unit [J∙x-­1] clearly indicates exergy per elementary entity. The unit [x] is a motive unit.


SI-units.png

Stating quantity values being pure numbers (p. 151)

Bureau International des Poids et Mesures (2019) The International System of Units (SI). 9th edition:117-216 ISBN 978-92-822-2272-0. - »Open Access pdf«
There are also some quantities that cannot be described in terms of the seven base quantities of the SI, but have the nature of a count. Examples are a number of molecules, a number of cellular or biomolecular entities (for example copies of a particular nucleic acid sequence), or degeneracy in quantum mechanics. Counting quantities are also quantities with the associated unit one. The unit one is the neutral element of any system of units – necessary and present automatically. There is no requirement to introduce it formally by decision. Therefore, a formal traceability to the SI can be established through appropriate, validated measurement procedures (Section 2.3.3, p. 136).
As discussed in Section 2.3.3, values of quantities with unit one, are expressed simply as numbers. The unit symbol 1 or unit name “one” are not explicitly shown. SI prefix symbols can neither be attached to the symbol 1 nor to the name “one”, therefore powers of 10 are used to express particularly large or small values.
Quantities that are ratios of quantities of the same kind (for example length ratios and amount fractions) have the option of being expressed with units (m/m, mol/mol) to aid the understanding of the quantity being expressed and also allow the use of SI prefixes, if this is desirable (μm/m, nmol/mol). Quantities relating to counting do not have this option, they are just numbers.
The internationally recognized symbol % (percent) may be used with the SI. When it is used, a space separates the number and the symbol %. The symbol % should be used rather than the name “percent”. In written text, however, the symbol % generally takes the meaning of “parts per hundred”. Phrases such as “percentage by mass”, “percentage by volume”, or “percentage by amount of substance” shall not be used; the extra information on the quantity should instead be conveyed in the description and symbol for the quantity.
The term “ppm”, meaning 10-6 relative value, or 1 part in 106, or parts per million, is also used. This is analogous to the meaning of percent as parts per hundred. The terms “parts per billion” and “parts per trillion” and their respective abbreviations “ppb” and “ppt”, are also used, but their meanings are language dependent. For this reason the abbreviations ppb and ppt should be avoided.


References

Bioblast linkReferenceYear
Bureau International des Poids et Mesures (2019) The International System of Units (SI). 9th edition:117-216 ISBN 978-92-822-2272-0.2019
Cohen ER, Cvitas T, Frey JG, Holmström B, Kuchitsu K, Marquardt R, Mills I, Pavese F, Quack M, Stohner J, Strauss HL, Takami M, Thor HL (2008) Quantities, Units and Symbols in Physical Chemistry. IUPAC Green Book 3rd Edition, 2nd Printing, IUPAC & RSC Publishing, Cambridge.2008
Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. Bioenerg Commun 2020.2 (in prep).2020
Gnaiger Erich (2020) A X-mass Carol. Account of the elementaries of Body Mass Excess. MitoFit Preprint Arch 2020.4.v0.
Gnaiger Erich et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. doi:10.26124/bec:2020-0001.v1.2020
Mohr Peter J, Phillips William D (2015) Dimensionless units in the SI. Metrologia 52:40-7.2015


SI-units.png


Click to expand or collaps
Bioblast links: SI base units - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
Entity, count, and number, and SI base quantities / SI base units
SI-units.png
Quantity name Symbol Unit name Symbol Comment
elementary UX elementary unit [x] UX, UB; [x] not in SI
count NX elementary unit [x] NX, NB; [x] not in SI
number N - dimensionless = NX·UX-1
amount of substance nB mole [mol] nX, nB
electric current I ampere [A] A = C·s-1
time t second [s]
length l meter [m] SI: metre
mass m kilogram [kg]
thermodynamic temperature T kelvin [K]
luminous intensity IV candela [cd]
Fundamental relationships
» Avogadro constant
» Boltzmann constant
» elementary charge
» Faraday constant
» gas constant
SI and related concepts
» International System of Units
» International Union of Pure and Applied Chemistry, IUPAC
» entity
» quantity
» dimension
» format
» motive unit



Questions.jpg


Click to expand or collaps
Bioblast links: Normalization - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>



MitoPedia concepts: Ergodynamics